After an explosion in a bio lab, the CSI team races to determine which nerve agent left one of their own unconscious, while the others explore a dangerous underground tunnel to find another CSI who got kidnapped during the blast.

The CSI team investigates the death of a local antique shop owner who died from an apparent gunshot wound that is missing one important clue - the bullet. Also, Max makes an important breakthrough in the ongoing case with Ocho from the robotics factory.

The CSI team investigates when a plastinated nervous system is found hanging above a local car dealership. Also, Chavez and Max search for a missing source in their ongoing investigation of the robotics factory.

When a fitness guru is found dead in a gym sauna and his soon to be son-in-law is found dead from an apparent hunting accident, the CSI team investigates to see if these deaths are unrelated tragic accidents or if they're connected.

The CSI team investigates a radioactive crime scene that left a father and son dead.

When a mechanic is found murdered in a dark factory, the CSI team investigates whether the perpetrator was human or a humanoid robot with an AI operating system.

As the CSI team investigates the death of a man visiting Las Vegas for a health and wellness convention, a fiery explosion traps Allie Rajan in the basement of an abandoned hospital.

With a new piece of evidence at play, Catherine Willows reopens an investigation from her past that never got solved after a violent attack left her hospitalized. Internal affairs begins questioning Folsom.

With their respected colleague Josh Folsom under arrest for the death of Kahn Schefter – the man responsible for killing Folsom’s mother – the CSI team combs through every crumb of forensic evidence to determine his innocence or guilt.